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Artificial Insemination: What It Is, How It Works, and Who Needs It

Dr. Manisha Acharya
Reviewed by Dr. Manisha Acharya ,
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This information has been reviewed and approved by an experienced fertility specialist at Indira IVF to provide accurate and up-to-date guidance for our readers.

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Last updated: July 09, 2025

Synopsis

Artificial insemination (AI) is one of the most common methods used to treat couples who are unable to conceive naturally. While it may now seem like a modern technique, artificial insemination has been practised since the early 1900s. However, even if the procedure has always taken the same basic approach to helping women become pregnant, that approach has become more advanced and precise over the years. It is a safe, proven, and minimally invasive option offered at advanced fertility centres. This article explains what artificial insemination is, how it works, who might benefit, the types of procedures available for consideration, and what to expect out of this process.

 

Introduction to Artificial Insemination

Artificial insemination is a fertility procedure wherein sperm is placed in a woman's reproductive tract to bring about fertilisation. Whereas in natural intercourse, sperm travels towards the egg on its own. AI keeps the sperm nearer to the egg, increasing the chances of fertilisation.

The inseminating physician will introduce the sperm through an insemination catheter - a thin, flexible tube and the female partner will undergo treatment twice: once at 12 hours and the second at 36 hours, after hormone medications are given. This method reduces the chances of fertilisation failure by placing a strong concentration of sperm at the time of peak ovulation. This timeframe is alerted through bloodwork and hormone medications.

Artificial insemination is preferred since it is less invasive and less expensive than In Vitro Fertilisation (IVF). Patients with male fertility problems, female ovulation disorders, etc., can greatly benefit from this method. Artificial insemination is performed under the supervision of fertility experts by employing the latest technology to maximise the success rates.

How Artificial Insemination Works

Artificial Insemination requires only a few precisely timed stages to obtain the highest chance of fertilisation. Semen collection, preparation and insemination into the uterus comprise a major part of the procedure.

Procedure Overview

  • Monitoring the Woman’s Cycle : Examining the body for indications that ovulation may occur is essential since timing is critical. The procedure is conducted during the most fertile period.
  • Sperm Collection and Preparation : Sperm is collected and later processed from either the partner or a donor. During washing, impurities are removed, and sperm with greater motility are preferred.
  • Insemination : Using a fine catheter, sperm is either inserted into the uterus or cervix.

Sperm Preparation and Timing

Sperm washing is crucial for removing seminal fluid, which could cause cramping or reactions in the uterus. By employing a tiny, highly concentrated sample of healthy sperm, the chances of getting pregnant increase.

Timing is equally important. Ovulation kits, blood tests, or ultrasounds may be used to pinpoint when ovulation is about to occur. Your doctor will probably have a plan outlining when your treatment will take place and what to anticipate.

IUI vs ICI

Aspect Intrauterine Insemination (IUI) Intracytoplasmic Sperm Injection (ICSI)
Placement of sperm Inside the uterus In a lab, directly injected into an egg
Success rate Higher High, particularly if it is for infertility in men.
Invasiveness Mildly invasive More intrusive (involves lab fertilisation and egg retrieval)
Commonly used for Unexplained infertility, male factor Extreme male infertility, extremely low-quality sperm, and prior IVF failures

Types of Artificial Insemination Procedures

Artificial insemination increases the chances of pregnancy by placing semen or concentrated sperm into the vagina, cervix, or uterus. The different types of artificial insemination include:

Intrauterine Insemination (IUI)

IUI is the most widely used method. The sperm is inserted directly into the uterus to increase the number of sperm reaching the fallopian tubes.

Suitable For:

  • Women with ovulation disorders.
  • Mild male infertility (low sperm count or motility).
  • Unexplained infertility

Procedure Steps:

  • Ovulation is tracked or stimulated.
  • Sperm is collected, washed, and inserted via catheter.
  • T
  • he woman may rest briefly before returning to normal activities.

Success Rates:

  • Roughly 10–20% per cycle, depending on age and health factors.

Intracytoplasmic Sperm Injection (ICSI)

Procedure & Effectiveness : The embryo is transferred after a sperm cell is directly inserted into an egg in a lab using Intracytoplasmic Sperm Injection (ICSI). This procedure is incredibly effective in resolving male infertility problems.

When it's in Use : Suggested for those with severe male factor infertility or those who have had failed IVF rounds in the past.

Suitable Patients : Couples who have poor motility, low sperm counts, or instances where traditional IVF has failed to succeed.

In Vitro Fertilisation (IVF)

Process & Success : The procedure and outcome include the retrieval of eggs, sperm fertilisation in a lab, and the transfer of one embryo into the uterus. Depending on age and health, the normal success rate for IVF is between 30% and 60%.

Indication : Suggested for endometriosis, elderly women, obstructed fallopian tubes, or unexplained infertility.

Ideal Candidates : Older couples, women with ovulation issues, and couples with unexplained infertility.

Who Needs Artificial Insemination

Artificial insemination is advised for people or couples with situations such as:

  • Ovulation Issues : Irregular or no ovulation decreases the odds of conception.
  • Male Fertility Problems : Low sperm count, poor motility, or problems with ejaculation.
  • Unexplained Infertility : Artificial insemination is often done as a first line of treatment for unexplained infertility. Medications that assist the ovaries to produce eggs are very commonly used in conjunction with artificial insemination.

AI is often the first line of treatment due to its affordability and ease compared to more complex techniques.

Risks and Side Effects of Artificial Insemination

While the use of AI is usually safe and comes with only mild side effects, potential issues include:

  • Light cramping or spotting after the procedure.
  • Artificial insemination by itself is not associated with an increased chance of getting pregnant with twins, triplets, or more children. This risk increases when fertility medications are used with IUI.
  • Mild bloating or mood changes associated with hormonal medications.

Other Considerations :

  • Emotional stress related to the possibility of cycles failing (not all cycles succeed).
  • Financial implications of multiple cycles if needed.

It will be helpful to engage with a fertility navigator to manage your expectations and to be aware of the whole rationale of the project.

Preparing for Artificial Insemination

Adequate planning increases the likelihood of success with artificial insemination. Steps to consider:

  • Consult a Specialist : Meet a reproductive health professional to discuss your medical history and complete fertility examinations.
  • Track Ovulation : Monitor ovulation through ovulation predictor kits, ultrasounds, or hormone testing.
  • Source Sperm : Consider when dealing with sperm via a partner sperm or donor sperm, review the screening and preparation of sperm.
  • Understand the Process : Gain understanding about the actual process (what's happening in your body) and prepare mentally and physically.

These aspects, especially when considering medical advice from clinics, will have a huge impact on your success rate.

Conclusion

Artificial insemination has enabled countless individuals to let their parenthood dreams become a reality. It offers a safe, trustworthy, and mainstream option for people going through difficulties with fertility. Whether there are medical reasons, personal choices, or if it is unexplained infertility, AI provides hope and access.

Our care team is committed to ensuring every patient gets unique and personalised care and support throughout their fertility journey. We advise everyone who is looking for artificial insemination to seek professional advice before taking the first steps towards creating their family.

Frequently Asked Questions About Artificial Insemination

Is artificial insemination painful?

How many cycles of artificial insemination are usually needed?

What steps are involved in preparing sperm for artificial insemination?

What is the cost of artificial insemination?

Why use artificial insemination?