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Adenomyosis: Symptoms, Diagnosis, and Treatment

Dr. Manisha Acharya
Reviewed by Dr. Manisha Acharya ,
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This information has been reviewed and approved by an experienced fertility specialist at Indira IVF to provide accurate and up-to-date guidance for our readers.

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Last updated: November 07, 2025

Synopsis

The purpose of this article is to empower women in their reproductive health decision-making by dissecting the causes, symptoms, consequences, etc. of adenomyosis. Adenomyosis is a condition that often causes heavy, painful periods, pelvic discomfort, and in some cases, difficulties in conceiving. This condition is associated with middle-aged women and those who have had several pregnancies or uterine surgery. The good news is that, with early diagnosis and proper treatment of adenomyosis, the symptoms can be controlled efficiently.

 

Introduction

In adenomyosis, endometrial tissue that is usually found in the uterus and is responsible for menstruation, begins to appear in the uterine muscle wall. This abnormal growth can lead to heavy or prolonged periods, intense cramps, pelvic pain, and even an enlarged uterus. In some cases, the symptoms of adenomyosis are so minor that they become difficult to detect. On the other hand, in some women, it can get to a point where the condition significantly impacts their everyday lives and fertility.

While not life-threatening, the quality of a woman's life can still be greatly compromised by the symptoms of adenomyosis, which include heavy bleeding and pain. However, the developments in diagnostic procedures and therapeutic methods have made it possible for women to receive unique care that is not only comforting in times of pain but also reassuring in terms of fertility planning.

What is Adenomyosis?

Adenomyosis is a condition where the tissue that normally lines the uterus (endometrium) starts growing into the muscular wall of the uterus (myometrium). These unusual cells make the uterine walls thicken, and quite often this will result in heavy periods, painful cramps, and pelvic discomfort. In some women, the condition may be so mild that it can go unnoticed for a long time without any symptoms. On the other hand, if symptoms become severe, it can not only lower the quality of life of a woman but also affect her fertility.

Comprehending adenomyosis will be easier if you understand the following:

  • Endometrial tissue grows into the uterine muscle.
  • Leads to heavy or extended bleeding.
  • Extreme menstrual pain and bloating may be caused by this condition.
  • It is quite likely that it may contribute to fertility problems in particular women.

Symptoms of Adenomyosis

It should be noted that the severity of adenomyosis symptoms varies. While some women might experience slight discomfort, others might go through severe pain.

The most frequent symptoms of the disease include:

  • Heavy or prolonged periods: One of the most common symptoms of adenomyosis is excessive bleeding, which can often result in anaemia and fatigue.
  • Severe menstrual cramps: Besides being very painful, cramps can aggravate with time, and the patient may feel uncomfortable.
  • Chronic pelvic pain: This pain is non-periodic and, in some cases, becomes so intense that the woman cannot do her regular activities, such as walking, going to the bathroom, or standing.
  • Bloating or enlarged uterus: The uterus may feel bulky, causing abdominal heaviness.
  • Pain during intercourse: The uterine changes, leading to discomfort or pain during intercourse.
  • Fertility issues: One of the reasons for infertility due to adenomyosis is the failure of implantation, as well as irregular cycles.

If these symptoms interfere significantly with your everyday activities, visiting a professional for evaluation is highly recommended.

Causes and Risk Factors

The exact causes of adenomyosis are not fully understood; however, doctors have identified several risk factors that might make it more likely that this problem will occur.

  • Age: Most cases of adenomyosis that are estrogen-dependent are found in women aged 40-50.
  • History of multiple pregnancies: Multiple pregnancies may trigger severe changes in the uterine wall.
  • Previous uterine surgery: In case of a history of surgeries on the uterus, like uterine fibroid removal or dilation and curettage (D&C).
  • Hormonal imbalances: The formation of aberrant tissues is mostly influenced by oestrogen.

The presence of these factors does not imply the presence of adenomyosis, but they can increase the risk of the disease, which is why regular check-ups are necessary.

Diagnosis of Adenomyosis

Since symptoms of adenomyosis are similar to those of fibroids or endometriosis, diagnosing it is difficult. Usually, a clinical evaluation and imaging tests are necessary.

Among the primary diagnostic techniques are:

  • Examining the pelvic region to find a uterus that is either enlarged or causes pain when touched.
  • An ultrasound scan to check the uterine wall at the time of initial assessment.
  • The use of MRI to do in-depth studies on tissue changes.
  • Disregarding other disorders like fibroids and endometriosis.

Early and correct adenomyosis diagnosis gives doctors the opportunity to suggest the best-fitting treatment plan.

Adenomyosis and Fertility

Adenomyosis is a condition that can lead to infertility with its progressive change in the uterine environment. Consequently, an embryo finds it difficult to attach and grow. Adenomyosis symptoms, like severe cramping and excessive bleeding, can also cause uterine malfunction and, consequently, affect the embryo's receptivity. When comparing adenomyosis vs endometriosis, it can be noticed that both issues have a negative impact on fertility, but adenomyosis is the one that directly occurs in the uterine wall; therefore, it can become the root problem for conception or pregnancy.

Despite these challenges, many women suffering from adenomyosis and infertility issues are still capable of getting pregnant. With proper treatment of adenomyosis, which can include both symptom-controlling medications and advanced therapies such as IVF, not only are the chances of conception greatly raised, but the pregnancy outcomes are also made healthier.

Treatment Options for Adenomyosis

There is no one particular solution for this problem. The best adenomyosis treatment will depend on the nature of the symptoms, the woman's age, and her wish for future fertility.

Medication Management

  • The doctor might recommend anti-inflammatory medications to alleviate the pain.
  • Hormonal therapies, such as birth control pills and intrauterine devices (IUDs), are meant to control adenomyosis by producing less estrogen.

Minimally Invasive Treatments

  • Procedures such as uterine artery embolisation and radiofrequency ablation reduce the pain-causing part of the organ, thus helping the patients without major surgery.

Surgical Options

  • A hysterectomy, involving the total surgical removal of the uterus, is the only and final solution to the problem of adenomyosis. It is a significant medical procedure, and it is only applied in cases of severe adenomyosis and people who are not planning to get pregnant in the future.

Fertility-Focused Treatment

  • Doctors sometimes use hormonal treatments in conjunction with assisted reproductive methods such as IVF to help women who want to become pregnant. Personalised adenomyosis care programs are designed to achieve a balance between symptom management and fertility preservation.

Why Choose Indira IVF for Adenomyosis Treatment?

Living with adenomyosis might be a tough task; however, professional guidance will definitely make the process smoother.

Here’s why Indira IVF is a trusted choice for adenomyosis treatment:

  • Our doctors are highly skilled in diagnosing adenomyosis symptoms and recommending the right treatment plan aimed at individual cases of women.
  • We employ high technology in diagnosing adenomyosis versus endometriosis to achieve the most accurate result.
  • Our main focus is creating a plan that manages the pain, controls the bleeding and improves fertility in the case of adenomyosis.
  • We aim at complete relief from adenomyosis symptoms and thus use surgical procedures as the last resort when we perform operations such as advanced laparoscopy and hysteroscopy.
  • In addition to taking care of your family planning needs, Indira IVF offers you assistance for lifestyle modifications and fertility therapies like IVF, which come with a cohesive and patient-centred treatment strategy.

Book a Consultation

If heavy periods, pelvic pain, or fertility difficulties are affecting your life, it’s time to seek medical advice. Just as in most cases, early diagnosis and proper treatment lead to good recoveries and restoration of quality of life.

Book an Appointment Now

Frequently Asked Questions

Is adenomyosis the same as endometriosis?

Can adenomyosis cause infertility?

Can adenomyosis be cured permanently?

What age group is most affected?

Does adenomyosis always need surgery?